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To minimise severe flare-up, slow withdrawal is recommended by decreasing how often the topical steroid is applied and choosing another topical steroid that is less potentand with less immediate effect .4.4. Other Considerations for Patients with PSE There is some concern about the use of non-steroidal anti-inflammatory drugs in patients with PCS and an allergic reaction to this drug. Non-steroidal anti-inflammatory drugs (NSAIDS) are relatively new treatments for PSE and have been used frequently in patients for a number of years . It is not clear whether non-steroidal anti-inflammatory drugs affect PCS severity, but anecdotally they have been associated with reduced severity with PCS, in most cases significantly . Despite some conflicting studies, NSAIDs have been shown to be less likely to cause allergic rhinitis, but not for PSE and so the overall consensus in most situations is that they should not be used in patients with PCS.Further information is available from the Cochrane Library of Controlled Trials: http://www.sagepub.com/cochrane/search/display/36/1Related Article: